BDBM50526812 CHEMBL4441524

SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)[C@H]2CC[C@H](O)CC2)C(=O)N[C@@H](CC2=CCCC2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=ONVNUBAXWAHVEF-WNVKXBHVSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50526812   

TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526812(CHEMBL4441524)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526812(CHEMBL4441524)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of LMP2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526812(CHEMBL4441524)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of LMP2 in human MOLT4 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526812(CHEMBL4441524)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of 20S proteasome beta 1i (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Mus musculus)
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50526812(CHEMBL4441524)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of LMP2 in mouse A20 cells by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed